10号染色体开放阅读框4抗体

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商品详情：

英文名称：FRA10AC1
中文名称：10号染色体开放阅读框4抗体
别    名:Chromosome 10 open reading frame 4; F26C11.1 like; C10orf4; FRA10AC1 protein; Fragile site 10q23.3; PRO2972; Protein FRA10AC1; Rare folic acid type fragile site FRA(10)(q23.3) candidate gene 1; F10C1_HUMAN.

研究领域:细胞生物  免疫学  神经生物学

抗体来源:Rabbit

克隆类型:Polyclonal

交叉反应:Human,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )

产品应用:WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理论分子量:38kDa

细胞定位:细胞核

性    状:Liquid

浓    度:1mg/ml

免 疫 原:KLH conjugated synthetic peptide derived from human C10orf4: 101-200/315

亚    型:IgG

纯化方法:affinity purified by Protein A

缓 冲 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

注意事项:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
10号染色体开放阅读框4抗体产品介绍:The protein encoded by this gene is a nuclear phosphoprotein of unknown function. This gene contains a tandem CGG repeat region within a CpG island that normally consists of 8-14 repeats but can expand to over 200 repeats. The repeat region is within the 5' UTR of some transcript variants, but is intronic to another variant. The expanded repeat allele is a fragile site and becomes hypermethylated, causing a reduction in gene expression. A disease phenotype has not been associated with expanded alleles. This gene is found within the rare FRA10A folate-sensitive fragile site. [provided by RefSeq, Dec 2016]

Subcellular Location:

Nuclear.

Tissue Specificity:

Ubiquitously expressed with higher expression in brain, heart, skeletal muscle, kidney and liver.