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商品详情:
英文名称:ZCCHC24/C10orf56
中文名称:10号染色体开放阅读框56抗体
别 名:C10orf56; Chromosome 10 open reading frame 56; Zinc finger CCHC domain-containing protein 24; Zinc finger, CCHC domain containing 24.
研究领域:细胞生物 免疫学 锌指蛋白 表观遗传学
抗体来源:Rabbit
克隆类型:Polyclonal
交叉反应: Human, (predicted: Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Zebrafish, )
产品应用:WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量:27kDa
细胞定位:细胞核
性 状:Liquid
浓 度:1mg/ml
免 疫 原:KLH conjugated synthetic peptide derived from human ZCCHC24/C10orf56: 101-200/241
亚 型:IgG
纯化方法:affinity purified by Protein A
缓 冲 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件:Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
10号染色体开放阅读框56抗体产品介绍: ZCCHC24 is a 241 amino acid protein that contains one CCHC-type zinc finger, suggesting a role in transcriptional regulation. The gene encoding ZCCHC24 maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious.